Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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6,601 – 6,615 of 60,541 results

6,601

Cayman Chemical 5-fluoro 7-QUPAIC, Purity: ≥98%, CAS: 2748300-92-5, 5 mg

An analytical reference standard categorized as a synthetic cannabinoid; intended for research and forensic applications

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6,602

Meso Scale Discovery Total Akt Kit

The Meso Scale Discovery Total Akt Kit is a 96-well plate assay for measuring total Akt protein in cell and tissue lysates It uses MSD s SULFO-TAG labels and multi-array technology for a fast sensitive and reproducible quantification method The kit includes a streptavidin plate with a capture antibody a detection antibody with ruthenium sample diluent wash buffer read buffer and cell lysate controls It has a sensitivity of 1-2 ng/mL and a range up to 10 000 pg/mL compatible with various buffers and detergents ideal for high-throughput Akt screening

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6,603

Medchemexpress LLC Polycarbophil | 9003-97-8 | 500 MG

Polycarbophil is an orally active hydrophilic polymer that achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces. It prolongs compound retention time and regulates compound release through swelling properties, making it effective in relieving constipation and diarrhea.

Orally active hydrophilic polymer
Achieves bioadhesion through hydrogen bonding
Prolongs compound retention time
Regulates compound release through swelling properties
Relieves constipation
Relieves diarrhea

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6,604

Cayman Chemical Albiflorin, Purity: ≥98%, CAS: 39011-90-0, 5 mg

A monoterpene glycoside with diverse biological activities; prevents increases in ROS, nitrotyrosine, and mitochondrial superoxide levels induced by antimycin A in MC3T3-E1 osteoblastic cells at 0.1 and 1 μM; increases the paw withdrawal threshold and decreases spinal cord levels of IL-1β, IL-6, TNF-α, and CXCL1 in rat model of CCI-induced neuropathic pain at 50 mg/kg; decreases the time spent immobile in the forced swim and tail suspension tests in mice at 3.5, 7, and 14 mg/kg, indicating antidepressant-like effects

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6,605

Cayman Chemical ANTIBODY TPU-0037C 500ug

A Streptomyces metabolite; structurally similar to lydicamycin; active against Gram-positive bacteria (MICs = 0.39-3.13 UG/ml), including methicillin-resistant S. aureus strains (MIC = 3.13 UG/ml); ineffective against Gram-negative bacteria (MICs = >50 UG/ml)

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6,606

Medchemexpress LLC N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamide | 604769-01-9 | MFCD13186898 | 99.1% | 413.45 g·mol⁻¹ | C19H19N5O4S | 1 ML

Hydroxamate-based histone deacetylase (HDAC) inhibitor supplied as a 10 mM solution in DMSO for research use. It is intended for biochemical and cellular assays to study HDAC inhibition and related pathways. Provided with analytical documentation including a certificate of analysis and chromatographic data.

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6,607

Cayman Chemical Nepafenac, Purity: ≥98%, CAS: 78281-72-8, 10 mg

A prodrug from of amfenac; an inhibitor of PG synthase 1 (IC50 = 64.3 µM); inhibits the production of PGs in isolated rabbit iris/ciliary body; topical application prior to paracentesis reduces protein and PGE2 accumulation in a rabbit model of acute ocular inflammation at 0.1%

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6,608

Cayman Chemical Pridinol (hydrochloride), Purity: ≥98%, CAS: 968-58-1, 5 mg

An analytical reference standard categorized as a muscle relaxant; intended for research and forensic applications

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6,609

Cayman Chemical Dorsomorphin (hydrochloride), Purity: ≥98%, CAS: 1219168-18-9, 5 mg

A potent, reversible inhibitor of AMPK (Ki = 109 nM); dose-dependently inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6); downregulates the Akt/mTOR pathway to induce autophagy in U251 human glioma cells

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6,610

Cayman Chemical DUB-IN-2, Purity: ≥95% (mixture of cis/trans isomers), CAS: 924296-19-5, 10 mg

An inhibitor of USP8 (IC50 = 280 nM); selective for USP8 over USP7 (IC50 = >100 µM); increases the level of PD-L1 in H460 cells at 2 µM and PC-9 cells at 2 and 4 µM; decreases tumor weight, tumor size, and lung metastasis and increases CD8+ T cell numbers within the primary tumor in a 4T1 murine mammary carcinoma model at 1 mg/kg every other day, i.p., when combined with an anti-PD-L1 antibody and paclitaxel

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6,611

Cayman Chemical Cadazolid, Purity: ≥98%, CAS: 1025097-10-2, 1 mg

An oxazolidinone-type antibiotic; has activity against a panel of C. difficile strains (MICs = 0.125-0.5 μg/ml); inhibits toxin A and B formation in stationary-phase cultures and spore formation in late exponential cultures of the toxigenic C. difficile strain ATCC 9689; inhibits C. difficile protein synthesis (IC50s = 0.08-0.31 μg/ml); increases survival in a mouse model of CDAD at 1 and 10 mg/kg; increases survival in a hamster model of CDAD at >3 mg/kg

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6,612

Medchemexpress LLC Physalin B | 23133-56-4 | 1 MG

Physalin B, one of the major active steroidal constituents of Cape gooseberry, induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway. It also inhibits the ubiquitin-proteasome pathway and induces incomplete autophagic response in human colon cancer cells in vitro.

One of the major active steroidal constituents of Cape gooseberry
Induces cell cycle arrest
Triggers apoptosis in breast cancer cells
Modulates p53-dependent apoptotic pathway
Inhibits the ubiquitin-proteasome pathway
Induces incomplete autophagic response in human colon cancer cells in vitro

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6,613

Cayman Chemical BAY-1895344 (hydrochloride), Purity: ≥98%, 10 mg

An ATR inhibitor; inhibits proliferation in a panel of human tumor cell lines (mean IC50 = 78 nM); halts tumor growth in ovarian and colorectal mouse xenograft models and induces complete tumor remission in mantle cell lymphoma mouse xenograft models; exhibits synergistic anti-tumor activity with radium-223 in a mouse xenograft model of castration-resistant prostate cancer bone metastases

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6,614

Cayman Chemical Zingerone, Purity: ≥98%, CAS: 122-48-5, 25 g

A phenolic ketone; scavenges DPPH radicals in a cell-free assay (EC50 = 41.6 μmol); prevents myocardial expression of TNF-α, IL-1β, and IL-6 in rats following isoproterenol-induced myocardial infarction at 6 mg/kg per day; decreases 1,2-dimethylhydrazine-induced tumor incidence by 67% and aberrant crypt foci formation by 68.85% in rats at 20 mg/kg per day; decreases E. coli heat-labile enterotoxin-induced fluid accumulation in the ileal loop of mice at 10 mM

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6,615

Medchemexpress LLC Hexafluoro-diallylhexaflurobisphenol | 128481-73-2 | 97.4% | 5 MG

Hexafluoro-diallylhexaflurobisphenol is a synthetic Honokiol analogue used in biochemical and pharmacological research. It is a hexafluoro-substituted bisphenol derivative supplied as a high-purity oil for in vitro assays and medicinal chemistry studies.

Used as a Honokiol analogue for antioxidative and anticancer research.
High purity suitable for analytical and screening applications.
Small milligram pack sizes support early-stage assay work.
Molecular weight 416.36 g/mol and formula C21H18F6O2.
Oil form facilitates dissolution in organic solvents.

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Bioactive Small Molecules

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Meso Scale Discovery Total Akt Kit Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Polycarbophil | 9003-97-8 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamide | 604769-01-9 | MFCD13186898 | 99.1% | 413.45 g·mol⁻¹ | C19H19N5O4S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Physalin B | 23133-56-4 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Hexafluoro-diallylhexaflurobisphenol | 128481-73-2 | 97.4% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Meso Scale Discovery Total Akt Kit

Medchemexpress LLC Polycarbophil | 9003-97-8 | 500 MG

Medchemexpress LLC N-hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamide | 604769-01-9 | MFCD13186898 | 99.1% | 413.45 g·mol⁻¹ | C19H19N5O4S | 1 ML

Medchemexpress LLC Physalin B | 23133-56-4 | 1 MG

Medchemexpress LLC Hexafluoro-diallylhexaflurobisphenol | 128481-73-2 | 97.4% | 5 MG